The Security Mentor

You can scan it with your antivirus software, and you should, but any one antivirus program might miss something.

Most of the time, the right thing to do is to follow the wisdom you learned as a child about funny-smelling items from the fridge -- "when it doubt, throw it out".

If that's not an option or if you're just curious, and if the file is not confidential, there's a website that will scan your file with about a dozen antivirus engines. Too much trouble for regular use, but it's a good resource to know about.